Large animalin vivoevaluation of a binary blend polymer scaffold for skeletal tissue-engineering strategies; translational issues
نویسندگان
چکیده
منابع مشابه
fabricating electrospun poly(3-hydroxybutyrate)/hydroxyapatite nanocomposite scaffold for tissue engineering application
. در رســاله ی حاضر، ابتدا داربست نانوالیاف سه بعدی متخلخل به روش الگوبرداری تصویری شبیه سازی شد. با استفاده از طراحی آزمایش به روش تاگوچی پس از ساخت داربست های پلی (3- هیدروکسی بوتیرات) (p3hb) شناسایی رفتار پارامترهای موادی مثل لزجت سیال پلیمر، فراریت و رسانایی الکتریکی محلول پلیمری و پارامترهای دستگاهی مثل دبی حجمی سیال، ولتاژ الکتریکی و فاصله نازل تا جمع کننده صورت گرفت. بعد از محاسبه ی خصوص...
Scaffold Stiffness Influences Cell Behavior: Opportunities for Skeletal Tissue Engineering
Skeletal defects resulting from trauma, tumors, or abnormal development frequently require surgical treatment to restore normal tissue function. To overcome the limitations associated with conventional surgical treatments, several tissue engineering approaches have been developed. In particular, the use of scaffolds enriched with stem cells appears to be a very promising strategy. A crucial iss...
متن کاملSkeletal muscle tissue engineering: strategies for volumetric constructs
Skeletal muscle tissue is characterized by high metabolic requirements, defined structure and high regenerative potential. As such, it constitutes an appealing platform for tissue engineering to address volumetric defects, as proven by recent works in this field. Several issues common to all engineered constructs constrain the variety of tissues that can be realized in vitro, principal among th...
متن کاملIn vitro analysis of biodegradable polymer blend/hydroxyapatite composites for bone tissue engineering.
Blends of biodegradable polymers, poly(caprolactone) and poly(D, L-lactic-co-glycolic acid), have been examined as scaffolds for applications in bone tissue engineering. Hydroxyapatite granules have been incorporated into the blends and porous discs were prepared. Mechanical properties and degradation rates in vitro of the composites were determined. The discs were seeded with rabbit bone marro...
متن کاملCharacterization of Natural and Synthetic Polymer Blend Scaffolds for Tissue Engineering
Introduction: Tissue engineering provides an approach for generating functionally replaceable tissue parts. Biodegradable scaffolds are used to support and guide the in-growth of cells. The idea is that the scaffolding material eventually disappears leaving only the necessary healthy tissue in a topologically required form (1,2). While numerous biodegradable polymers have been investigated as c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Tissue Engineering and Regenerative Medicine
سال: 2015
ISSN: 1932-6254
DOI: 10.1002/term.2007